Prof. Geert van Loo

Member info

  • FACULTY:
    VIB-UGent
  • DEPARTMENT:
    Center for Inflammation Research/ dep. Molecular Biomedical Research
  • RESEARCH GROUP:
    Cellular and Molecular (Patho)physiology
  • FUNCTION:
    PI
  • WORK ADDRESS:
    Technologiepark 71 9052 Zwijnaarde
  • SUMMARY:
    Focus of our research is on the mechanistic understanding of signaling pathways (NF-kB, inflammasome, cell death, autophagy) that control inflammation. For these studies we use transgenic mice as a model to study gene function in vivo, both through Cre/LoxP-mediated gene targeting allowing tissue-specific gene deletion, and through CRISP/Cas technology to introduce specific mutations in vivo. These mice are characterized in several mouse models of chronic inflammatory pathology (including models for inflammatory bowel disease, rheumatoid arthritis, and multiple sclerosis) and inflammation-associated cancer.
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