Our lab leverages the power of chemistry, biotechnology and nanotechnology to engineer the immune system at better responding to internal threats such as cancer and external threats such as viral pathogens and lethal drug substances. In this context we aim to intervene at different levels in the process of innate immune activation, antigen presentation and the generation of adaptive immunity to clear or protect the host from a specific threat.
Frank Speleman is professor at the Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences. His main focus is the study of perturbed gene regulatory processes in paediatric cancer, more specifically neuroblastoma and T-ALL.
Nico Callewaert is group leader and director of the VIB-UGent Center for Medical Biotechnology and full professor in biochemistry and biotechnology at Ghent University. His research interests focus on the invention of technologies for medicine, proteins and sugars.
Kevin Braeckmans is Full Professor at Ghent University, faculty of Pharmaceutical Sciences. He is co-director of the Lab. Of General Biochemistry and Physical Pharmacy and group leader of the Biophotonics Research Group. His focus is on light-based technologies for investigating and facilitating drug delivery to cells and tissues, including for cell therapy applications.
Richard Hoogenboom is full professor at Ghent University and heads the supramolecular chemistry group that focuses on the development of advanced functional materials.
Prof. Dr. Annemieke Madder is heading the Organic and Biomimetic Chemistry Research Group specialized in the design and synthesis of modified peptides and nucleic acids and methods for their conjugation and labeling.
Prof. Jolanda van Hengel is heading the medical cell biology group. Her group focuses on the in vitro engineering of functional myocardium that mimics human heart tissue for analysis of myocardial function. Also her group tries to obtain a suitable stem cell type for in vitro meat production.
Kristl Vonck is Head of the Department ‘Head and Skin’ at Ghent University and full professor of neurology at the department of Neurology at Ghent University Hospital. Research interests include epilepsy, neuromodulation, bioelectronic medicine and neurophysiological home-monitoring of neurological disorders and is performed at the 4brain lab.
Frauke Coppieters is assistant professor within RARE-MED, a Ghent University multidisciplinary consortium for basic and translational research on precision medicine for rare diseases (Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences). Her research focuses on retinal disease modelling and new genetic therapies for inherited blindness.
Prof. Karen De Clerck is Full Professor at the Department of Materials, Textiles and Chemical Engineering at Ghent University. She is head of the Centre for Textile Science and Engineering (CTSE) and group leader of the Advanced Fiber Materials Research Group. She is an expert in the production, characterization and application of advanced fibrous materials.
Katrien Remaut is associate professor at the Lab General Biochemistry and Physical Pharmacy and focuses on nanoparticle-based approaches for ocular gene delivery and the treatment of peritoneal carcinomatosis.
Ruslan Dmitriev leads the Tissue Engineering and Biomaterials group at the Department of Human Structure and Repair, Ghent University.
Robrecht Raedt holds a 100% professorship at Ghent University (www.4BRAIN.be) and is director of the animal facility of the Faculty of Medicine and Health Sciences.