Our lab leverages the power of chemistry, biotechnology and nanotechnology to engineer the immune system at better responding to internal threats such as cancer and external threats such as viral pathogens and lethal drug substances. In this context we aim to intervene at different levels in the process of innate immune activation, antigen presentation and the generation of adaptive immunity to clear or protect the host from a specific threat.
Director of the Lab of General Biochemistry & Physical Pharmacy at UGent. Served as dean of his Faculty and member of Board of Directors of UGent. Has been a Guest Professor at various universities in Belgium and China and is Deputy Editor-in-Chief of the Journal of Controlled Release. His research is at the interface between drug delivery, biophysics and material sciences.
Kevin Braeckmans is Full Professor at Ghent University, faculty of Pharmaceutical Sciences. He is co-director of the Lab. Of General Biochemistry and Physical Pharmacy and group leader of the Biophotonics Research Group. His focus is on light-based technologies for investigating and facilitating drug delivery to cells and tissues, including for cell therapy applications.
Prof. Dr. Annemieke Madder is heading the Organic and Biomimetic Chemistry Research Group specialized in the design and synthesis of modified peptides and nucleic acids and methods for their conjugation and labeling.
Prof. Jolanda van Hengel is heading the medical cell biology group. Her group focuses on the in vitro engineering of functional myocardium that mimics human heart tissue for analysis of myocardial function. Also her group tries to obtain a suitable stem cell type for in vitro meat production.
Frauke Coppieters is assistant professor within RARE-MED, a Ghent University multidisciplinary consortium for basic and translational research on precision medicine for rare diseases (Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences). Her research focuses on retinal disease modelling and new genetic therapies for inherited blindness.
Sarah Vergult is an assistant professor at the Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University. She is partner of the Ghent University RARE-MED consortium, that aims to address missing heritability in rare disorders. She studies the role of the noncoding part of the genome in rare diseases, in particular in neurodevelopmental disorders and implements tools to functionally characterize candidate genes for neurodevelopmental disorders.
Katrien Remaut is associate professor at the Lab General Biochemistry and Physical Pharmacy and focuses on nanoparticle-based approaches for ocular gene delivery and the treatment of peritoneal carcinomatosis.
Frederic Acke is an otorhinolaryngologist with a PhD on genetic hearing loss. His main research focus is the exploration of mechanisms and innovative treatment strategies, including gene therapy, for inner ear disorders.
Prof. Peter Dubruel was appointed Professor in Polymer Chemistry and Biomaterials at Ghent University in 2006. Since then, he has been heading the Polymer Chemistry and Biomaterials Group (PBM) at Ghent University.
Robrecht Raedt holds a 100% professorship at Ghent University (www.4BRAIN.be) and is director of the animal facility of the Faculty of Medicine and Health Sciences.